- Trials with a EudraCT protocol (28)
- Paediatric studies in scope of Art45 of the Paediatric Regulation (0)
28 result(s) found for: Cancer of Unknown Primary Origin.
Displaying page 1 of 2.
EudraCT Number: 2008-005865-67 | Sponsor Protocol Number: PXD101-CLN17 | Start Date*: 2008-12-11 | |||||||||||
Sponsor Name:Topotarget A/S | |||||||||||||
Full Title: An open-label randomized phase II trial of belinostat (PXD101) in combination with carboplatin and paclitaxel (BelCaP) compared to carboplatin and paclitaxel in patients with previously untreated c... | |||||||||||||
Medical condition: Patients with previously untreated carcinoma of unknown primary | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: DK (Completed) DE (Completed) FR (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2018-004562-33 | Sponsor Protocol Number: CheCUP | Start Date*: 2019-12-04 | |||||||||||
Sponsor Name:University Heidelberg, Med. Fac. repr. by University Hospital and its Commercial Managing Director | |||||||||||||
Full Title: A phase II, open-label, non-randomized, multi-center study evaluating the efficacy and safety of nivolumab plus ipilimumab in patients with cancer of unknown primary site who are relapsed after or ... | |||||||||||||
Medical condition: Cancer of unknown primary site (CUP-Syndrome), relapsed/refractory to platinum-based chemotherapy | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: DE (Prematurely Ended) | |||||||||||||
Trial results: View results |
EudraCT Number: 2017-004163-12 | Sponsor Protocol Number: RP2017-001 | Start Date*: 2018-01-28 | |||||||||||
Sponsor Name:ReposPharma | |||||||||||||
Full Title: A phase 2a TDM-guided clinical study on the safety and efficacy of mebendazole in patients with advanced gastrointestinal cancer or cancer of unknown origin | |||||||||||||
Medical condition: Squamous cell cancer or adenocarcinoma, including primary cancer of the liver, of the gastrointestinal tract or cancer of unknown origin | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: SE (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2005-001912-38 | Sponsor Protocol Number: ACR-CMOD / 2005-2 | Start Date*: 2006-01-11 |
Sponsor Name:ACROSS | ||
Full Title: PHASE II TRIAL OF THE COMBINATION OF GEMCITABINE AND OXALIPLATIN IN THE TREATMENT OF PATIENTS WITH METASTATIC ADENOCARCINOMA OF UNKNOWN PRIMARY SITE Estudio fase II de la combinación de gemcitabina... | ||
Medical condition: METASTATIC ADENOCARCINOMA OF UNKNOWN PRIMARY SITE | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: ES (Ongoing) | ||
Trial results: (No results available) |
EudraCT Number: 2014-005018-47 | Sponsor Protocol Number: 008-IRCC-10IIS-14 | Start Date*: 2015-04-08 | |||||||||||
Sponsor Name:FONDAZIONE DEL PIEMONTE PER L'ONCOLOGIA IRCCS | |||||||||||||
Full Title: A PHASE II, RANDOMIZED, MULTICENTER STUDY TO ASSESS THE EFFICACY OF NAB-PACLITAXEL-BASED DOUBLET AS FIRST LINE THERAPY IN PATIENTS WITH CANCER OF UNKNOWN PRIMARY (CUP): the AGNOSTOS trial | |||||||||||||
Medical condition: Cancers of Unknown Primary (CUP) | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: IT (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2019-001546-18 | Sponsor Protocol Number: GETNE-T1913 | Start Date*: 2019-08-19 | |||||||||||||||||||||||||||||||||||||||||
Sponsor Name:Grupo Español de Tumores Neuroendocrinos y Endocrinos (GETNE) | |||||||||||||||||||||||||||||||||||||||||||
Full Title: A phase II study of Platinum-doublet chemotherapy in combination with nivolumab as first-line treatment, in subjects with unresectable, locally advanced or metastatic G3 Neuroendocrine Neoplasms (N... | |||||||||||||||||||||||||||||||||||||||||||
Medical condition: Unresectable, locally advanced or metastatic G3 Neuroendocrine Neoplasms (NENs) of the gastroenteropancreatic (GEP) tract or of unknown (UK) origin. | |||||||||||||||||||||||||||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||||||||||||||||||||||||||||||||
Trial protocol: ES (Ongoing) | |||||||||||||||||||||||||||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2021-005481-18 | Sponsor Protocol Number: BNT142-01 | Start Date*: 2022-04-28 | ||||||||||||||||||||||||||||||||||||
Sponsor Name:BioNTech SE | ||||||||||||||||||||||||||||||||||||||
Full Title: First-in-human, open-label, multicenter, Phase I/IIa, dose escalation trial with expansion cohorts to evaluate safety and preliminary efficacy of BNT142 in patients with CLDN6-positive advanced sol... | ||||||||||||||||||||||||||||||||||||||
Medical condition: Claudin 6 (CLDN6)-positive advanced solid tumors | ||||||||||||||||||||||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||||||||||||||||||||||
Trial protocol: ES (Ongoing) | ||||||||||||||||||||||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2019-004323-20 | Sponsor Protocol Number: BNT211-01 | Start Date*: 2020-06-30 | |||||||||||||||||||||||||||||||||||||||||
Sponsor Name:BioNTech Cell & Gene Therapies GmbH | |||||||||||||||||||||||||||||||||||||||||||
Full Title: Phase 1/2a, first-in-human, open-label, dose escalation trial with expansion cohorts to evaluate safety and preliminary efficacy of CLDN6 CAR-T with or without CLDN6 RNA-LPX in patients with CLDN6-... | |||||||||||||||||||||||||||||||||||||||||||
Medical condition: CLDN6-positive relapsed or refractory advanced solid tumors | |||||||||||||||||||||||||||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||||||||||||||||||||||||||||||||
Trial protocol: DE (Ongoing) NL (Ongoing) SE (Ongoing) | |||||||||||||||||||||||||||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2018-001327-39 | Sponsor Protocol Number: C/37/2017 | Start Date*: 2018-11-05 |
Sponsor Name:Imperial College London | ||
Full Title: A Phase II, Two-Stage, Trial of Pembrolizumab in Cancer of unknown primary - CUPem | ||
Medical condition: CUP, Cancer of Unknown Primary | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: GB (GB - no longer in EU/EEA) | ||
Trial results: (No results available) |
EudraCT Number: 2016-002858-20 | Sponsor Protocol Number: ESR-15-11561-61/DUNE | Start Date*: 2017-03-02 | |||||||||||
Sponsor Name:GETNE (Grupo Español de Tumores Neuroendocrinos) | |||||||||||||
Full Title: A phase II study of durvalumab (MEDI4736) plus tremelimumab for the treatment of patients with advanced neuroendocrine neoplasms of gastroenteropancreatic or lung origin (the DUNE trial). | |||||||||||||
Medical condition: Advanced neuroendocrine neoplasms of gastroenteropancreatic or lung origin. | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: ES (Ongoing) | |||||||||||||
Trial results: View results |
EudraCT Number: 2017-002767-17 | Sponsor Protocol Number: D0816C00020 | Start Date*: 2017-12-14 | |||||||||||
Sponsor Name:AstraZeneca AB | |||||||||||||
Full Title: A Phase IIIb, Single-arm, Open-label Multicentre Study of Olaparib Maintenance Monotherapy in Platinum Sensitive Relapsed non-Germline BRCA Mutated Ovarian Cancer Patients who are in Complete or Pa... | |||||||||||||
Medical condition: Non Germline BRCA Mutated Ovarian Cancer | |||||||||||||
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Population Age: Adults, Elderly | Gender: Female | ||||||||||||
Trial protocol: CZ (Completed) SI (Completed) BG (Completed) GB (GB - no longer in EU/EEA) NL (Completed) ES (Completed) BE (Completed) AT (Completed) SE (Completed) PT (Completed) NO (Completed) DK (Completed) FI (Completed) PL (Completed) IT (Completed) RO (Ongoing) | |||||||||||||
Trial results: View results |
EudraCT Number: 2004-004333-34 | Sponsor Protocol Number: EORTC 55041 | Start Date*: 2005-09-20 | |||||||||||
Sponsor Name:European Organisation for Research and Treatment of Cancer | |||||||||||||
Full Title: A randomized, multicentre, phase III study of Erlotinib versus observation in patients with no evidence of disease progression after first line, platinum-based chemotherapy for high-risk Stage I an... | |||||||||||||
Medical condition: Histologically confirmed high-risk FIGO stage I (grade 3, or aneuploid grade 1 or 2, or clear cell), or Stages II-IV ovarian epithelial, primary peritoneal, and fallopian tube cancer. | |||||||||||||
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Population Age: Adults, Elderly | Gender: Female | ||||||||||||
Trial protocol: BE (Completed) ES (Completed) IT (Completed) AT (Completed) GB (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2016-005197-35 | Sponsor Protocol Number: S1404 | Start Date*: 2017-06-06 |
Sponsor Name:Irish Clinical Oncology Research Group CLG, trading as Cancer Trials Ireland | ||
Full Title: A Phase III Randomized Trial Comparing Physician/Patient Choice of Either High Dose Interferon or Ipilimumab to MK-3475 (Pembrolizumab) in Patients with High Risk Resected Melanoma. | ||
Medical condition: High risk resected melanoma. | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: IE (Ongoing) | ||
Trial results: (No results available) |
EudraCT Number: 2020-000549-15 | Sponsor Protocol Number: S63678 | Start Date*: 2020-08-05 |
Sponsor Name:University Hospitals Leuven | ||
Full Title: Al18F-NOTA-octreotide PET imaging of the somatostatin receptor in neuroendocrine tumors | ||
Medical condition: Neuroendocrine tumors | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: BE (Completed) | ||
Trial results: View results |
EudraCT Number: 2015-003602-16 | Sponsor Protocol Number: PM1183-A-014-15 | Start Date*: 2022-08-18 | |||||||||||
Sponsor Name:PHARMA MAR, S.A. SOCIEDAD UNIPERSONAL | |||||||||||||
Full Title: Phase I/II, Multicenter, Open-label, Clinical and Pharmacokinetic Study of Lurbinectedin in Combination with Irinotecan in Pretreated Patients with Selected Advanced Solid Tumors. | |||||||||||||
Medical condition: Selected Advanced Solid Tumors | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: IT (Ongoing) DE (Ongoing) AT (Completed) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2011-005539-22 | Sponsor Protocol Number: GO28076 | Start Date*: 2012-10-08 | ||||||||||||||||||||||||||
Sponsor Name:Genentech, Inc. | ||||||||||||||||||||||||||||
Full Title: A PHASE II, OPEN-LABEL, RANDOMIZED STUDY OF MEHD7945A VERSUS CETUXIMAB IN PATIENTS WITH RECURRENT/METASTATIC SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK WHO HAVE PROGRESSED DURING OR FOLLOWING PLA... | ||||||||||||||||||||||||||||
Medical condition: Head and neck cancer of squamous cell origin | ||||||||||||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||||||||||||
Trial protocol: BE (Completed) DE (Completed) GB (Completed) ES (Completed) HU (Completed) IT (Completed) BG (Completed) | ||||||||||||||||||||||||||||
Trial results: View results |
EudraCT Number: 2016-004161-68 | Sponsor Protocol Number: AG013-ODOM-201 | Start Date*: 2018-10-31 | |||||||||||
Sponsor Name:Oragenics, Inc. | |||||||||||||
Full Title: A Phase 2, multi-center, randomized, double-blind, placebo-controlled study to assess the safety and efficacy of topically-applied AG013 for the attenuation of oral mucositis in subjects with cance... | |||||||||||||
Medical condition: Oral mucositis (OM) induced by chemoradiation therapy (CRT) used for the treatment of head and neck cancers (HNC) | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: BE (Completed) DE (Prematurely Ended) GB (GB - no longer in EU/EEA) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2016-001925-15 | Sponsor Protocol Number: ISS20159321 | Start Date*: 2018-10-22 | |||||||||||||||||||||
Sponsor Name:Alcedis GmbH | |||||||||||||||||||||||
Full Title: Evaluation of immunological effects of the RANKL-inhibitor Denosumab when administered concurrently with PD1-blocking antibodies (Nivolumab, Pembrolizumab) in patients with metastatic malignant me... | |||||||||||||||||||||||
Medical condition: Metastatic malignant melanoma | |||||||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||||||||||||
Trial protocol: DE (Completed) | |||||||||||||||||||||||
Trial results: View results |
EudraCT Number: 2014-004944-37 | Sponsor Protocol Number: MK-3475-054-07 | Start Date*: 2015-09-22 | |||||||||||
Sponsor Name:Merck Sharp & Dohme LLC, a Subsidiary of Merck & Co. Inc | |||||||||||||
Full Title: Adjuvant immunotherapy with anti-PD-1 monoclonal antibody Pembrolizumab (MK-3475) versus placebo after complete resection of high-risk Stage III melanoma: A randomized, double-blind Phase 3 trial o... | |||||||||||||
Medical condition: Stage III melanoma (AJCC R0) with histologically confirmed cutaneous melanoma metastatic to lymph node, classified as (AJCC, 2010): Stage IIIA with metastasis > 1 mm; any Stage IIIB or IIIC (no in-... | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: SE (Ongoing) GB (GB - no longer in EU/EEA) DE (Ongoing) PT (Ongoing) ES (Ongoing) DK (Ongoing) AT (Ongoing) BE (Ongoing) NL (Ongoing) PL (Ongoing) FI (Ongoing) IT (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2007-001974-10 | Sponsor Protocol Number: CA184-029 | Start Date*: 2009-03-13 | |||||||||||
Sponsor Name:Bristol-Myers Squibb International Corporation | |||||||||||||
Full Title: Adjuvant immunotherapy with anti-CTLA-4 monoclonal antibody (ipilimumab) versus placebo after complete resection of high-risk Stage III melanoma: A randomized, doubleblind Phase 3 trial of the EORT... | |||||||||||||
Medical condition: High Risk Stage III melanoma | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: GB (Completed) BE (Completed) IT (Completed) SE (Completed) FI (Completed) CZ (Completed) DK (Completed) DE (Completed) ES (Completed) FR (Completed) AT (Completed) NL (Completed) | |||||||||||||
Trial results: View results |
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